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PubMed PMID: 4696188

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These broad influences support skin health through multiple complementary pathways

It was taken at the Sachs Forum in Zurich, where Marc was presenting

Finally, data from mouse studies show that IgG accumulates in white adipose tissue in an FcRn-dependent manner, and that knocking down the receptor by an antisense oligonucleotide targeting the encoding FCGRT gene or deleting expression of FcRn from myeloid cellseffectively turning macrophages into degradative sinks for IgG [381]surprisingly improves metabolic function in mice with diet-induced obesity [382]

The oral route is particularly relevant for gastrointestinal applications because it delivers the peptide directly to the tissues where it is needed